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Academic background
- 1997 – 1998 Research Scientist, Exploratory Research Project on Behavioral Genetics (PI: Dr. Chankyu Park), Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Taejon, South Korea
Project title: Genetic linkage analyses on behavioral traits of Canis familiaris
- 1996 – 1997 Research Scientist, Environmental Research Team, SK Corporation, Taejon, South Korea
Project title: Research and Development of microbiological methods for the reclamation of petroleum contamination sites
- M.S. (1996) in Biological Sciences, Korea Advanced Institute of Science and Technology
Thesis title: Disruption in the protein translocation machinery and the lethality caused by the expression of RbsR-RbsB fusion protein in E. coli (Advisor: Prof. Chankyu Park)
- B.S. (1994) in Life Science, Korea Advanced Institute of Science and Technology
Thesis title: Modular Screening for transcriptional regulators of E. coli ackA and pta genes (Advisor: Dr. Chankyu Park)
Research interests
1. Molecular evolutionary genetics and genomics in insect sex determination and sociality
• Molecular mechanism and evolution of the complementary sex determination system in honey bees
• Molecular evolution of the sex-determination pathways in insects
• Genetic/genomic bases of honey bee sociality, particularly evolution of sensory systems, inter- and intra-caste communication, and innate immunity
2. Comparative and evolutionary genomics of gene family
• Origin and evolution of the ribonuclease A gene superfamily
• Adaptive evolution by gene duplication and functional diversification of the superfamily
Mentor
Jianzhi (George) Zhang
Recent publications
Cho, S., Huang, Z. Y., and Zhang, J. (2007) Sex-specific splicing of the honey bee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway, Genetics in press.
Cho, S., and Zhang, J. (2007) Zebrafish ribonucleases are bactericidal: Implications for the origin of the vertebrate RNase A superfamily, Molecular Biology and Evolution 24(5): 1259-68.
Cho, S., Huang, Z. Y., Green, D. R., Smith, D. R., and Zhang, J. (2006) Evolution of the complementary sex-determination gene of honey bees: balancing selection and trans-species polymorphisms. Genome Research 16: 1366-1375.
Cho, S., and Zhang, J. (2006) Ancient expansion of the ribonuclease A superfamily revealed by genomic analysis of placental and marsupial mammals. Gene 373: 116-125.
Cho, S., Beintema, J. J., and Zhang, J. (2005) The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Genomics 85(2): 208-220.
Cho, S., Jin, S.-W., Cohen, A. B., and Ellis, R. E. (2004). A phylogeny of Caenorhabditis reveals frequent loss of introns during nematode evolution. Genome Research 14(7):1207-1220.
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