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Fields of study
Molecular evolution
Research interests
It has been proposed that evolutionary changes at the morphological level are more often due to alterations of gene expression than protein sequences. However, the patterns and mechanisms of gene expression evolution are poorly understood. The main goal of my current research is to investigate the evolution of genes at the transcriptional level. I am also interested in other topics of mammalian genome evolution.
Academic background
M.Sci. in Zoology, National Taiwan University, Taipei, Taiwan (2002) B.Sci. in Biology, National Taiwan Normal University, Taipei, Taiwan (1998)
Advisor
Jianzhi (George) Zhang
Lab Website
Jianzhi (George) Zhang Lab home page
News
EEB bragging rights
Hearty congratulations to Ben-Yang Liao, Ph.D. candidate, for receiving the Rackham Graduate School Pre-doctoral Fellowship for 2007. Liao studies molecular evolution in Professor Jianzhi (George) Zhang's lab.
Recent publications
Ben-Yang Liao and Jianzhi Zhang. 2008. Co-expression of linked genes in mammalian genomes is generally disadvantageous. Molecular Biology & Evolution, in press.
Ben-Yang Liao and Jianzhi Zhang. 2008. Null mutations in human and mouse orthologs frequently result in different phenotypes. Proc. Natl. Acad. Sci. USA, in press.
Meng-Shin Shiao, Ben-Yang Liao, Manyuan Long and Hon-Tsen Yu. 2008. Adaptive evolution of the insulin two-gene system in mouse. Genetics 178: 1683-1691.
Ben-Yang Liao and Jianzhi Zhang. 2007. Mouse duplicate genes are as essential as singleton genes. Trends in Genetics. 23: 378-381.
Ben-Yang Liao, Nicole M. Scott and Jianzhi Zhang. 2006. Impacts of gene essentiality, expression pattern, and gene compactness on the evolutionary rate of mammalian proteins.
Molecular Biology & Evolution. 23: 2072-2080.
Ben-Yang Liao and Jianzhi Zhang. 2006. Low rates of expression-profile divergence in highly-expressed genes and tissue-specific genes during mammalian evolution. Molecular Biology & Evolution. 23: 1119-1128.
Ben-Yang Liao and Jianzhi Zhang. 2006. Evolutionary conservation of expression profiles between human and mouse orthologous genes. Molecular Biology & Evolution. 23: 530-540.
Ben-Yang Liao, Yu-Jung Chang, Jan-Ming Ho and Ming-Jing Hwang. 2004. The UniMarker (UM) method for synteny mapping of large genomes. Bioinformatics 20: 3156-65.
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